Louise Marie Loeber was born on May 3, 1894, in Amsterdam and grew up in a wealthy neighbourhood.
Her parents, who were passionate art lovers, let her follow paint classes with August LeGras and Co Breman. Between 1915 and 1918 she studied at the Rijksacademie in Amsterdam under the guidance of C.L. Dake and between 1919 and 1920 she was taught by Hans van Santen from Laren. Ze meets painter/writer Toon Verhoef who shows her Cubism and De Stijl. Verhoef shows her the way of naturalism towards the modern abstracted environment. In her works from between 1920-1921, the first signs of abstracting forms and fewer colours become visible. At the art trader Sal Slijper she studies the works of Piet Mondrian. Under influence from Verhoef, she strives for a link between modern art and socialism.

Loeber wants her work to be accessible by anybody and after a visit to the Bauhaus in 1927 she becomes a member of the “Socialistische Kunstenaarskring”(socialistic art ring). Like her neighbour Bart van der Leck she considers completely abstract art as elitist and the strongly abstracted reality remains her guiding principle. She was a member of the Vereniging van Beeldende Kunstenaars ‘Laren-Blaricum’. She married the socialistic artist Dirk Koning in 1931.

Lou Loeber died on May 3, 1983, in Amsterdam.